Astounding Stories of Super-Science, August 1930

Bell snarled wordlessly, but if one had noticed his eyes they would have been seen to be curiously cool and alert and waiting. The Master leaned forward, and for once spoke seriously, almost reverently. "There shall be a forward step, Senores, in the race of men. Do you know the difference between the brain of a man and that of an anthropoid ape? It consists only of a filmy layer of cortex, a film of gray nerve cells which the ape has not. And that little layer creates the difference between ape and man. And I have discovered more. My little medicine acts upon that film. Administered in the tiny quantities I have given to my slaves, it has no perceptible effect. It is merely a compound of a vegetable substance and a synthetic organic base. It is not excreted from the body. Like lead, it remains always in solution in the blood. But in or out of the blood it changes, always, to the substance which causes murder madness. Fresh or changed, my little medicine acts upon the brain." He smiled brightly upon them. "But though in tiny quantities it has but little effect, in larger quantities--when fresh it makes the functioning of the gray cells of the human brain as far superior to the unmedicated gray cells, as those human gray cells are to the white cells of the ape! That is what I have to offer to the human race! Intelligence for every man, which shall be as the genius of the past!"