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Dose, as a deobstruent and alterative, from one to five grains, daily; as a cathartic, from five to fifteen grains; to produce ptyalism, or salivation, from one to two grains, in a pill, with a quarter of a grain of opium, night and morning. Caution.--When taking calomel, exposure to cold or dampness should be guarded against, as such an imprudence would bring out an eruption of the skin, attended with fever. When this does occur, leave off the calomel, and give bark, wine, and purgatives; take a warm bath twice a day, and powder the surface of the body with powdered starch. 714. Tonics. Tonics are given to improve the tone of the system, and restore the natural energies and general strength of the body. They consist of bark, quassia, gentian, camomile, wormwood, and angostura bark. 715. Quassia Quassia is a simple tonic, and can be used with safety by any one, as it does not increase the animal heat, or quicken the circulation. Used internally, in the form of infusion, it has been found of great benefit in indigestion and nervous irritability, and is useful after bilious fevers and diarrhoea. Dose, of the infusion, from one and a half to two ounces, three times a day. 716. Gentian Gentian is an excellent tonic and stomachic; but when given in large doses, it acts as an aperient. It is used internally in all cases of general debility, and when combined with bark is used in intermittent fevers. It has also been employed in indigestion, and it is sometimes used, combined with sal volatile, in that disease; but, at other times alone, in the form of infusion. After diarrhoea, it proves a useful tonic. Its infusion is sometimes applied externally to foul ulcers.