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Dose, of the extract, from five to fifteen grains; of the compound extract, from five to fifteen grains; of the compound colocynth pill, the best of all its preparations, from ten to twenty grains. 742. Buckthorn Buckthorn is a brisk purgative for children in the form of syrup. Dose of the syrup, from one to six drachms. 743. Aloes Aloes is a purgative and cathartic in large, and tonic in smaller doses. Dose, of powder, from two to ten grains, combined with soap, bitter extracts, or other purgative medicines, and given in the form of pills; of the compound pill, from five to twenty grains; of the pill of aloes and myrrh from five to twenty grains; of the tincture, from four drachms to one ounce; of the compound tincture, from one to four drachms; of the extract, from six to ten grains; of the compound decoction, from four drachms to two ounces.